Dr. Hershenson's publications on PubMed

Dr. Hershenson's publications on Michigan Research Experts

Selected Publications

  1. Newcomb DC, Sajjan US, Nagarkar DR, Wang Q, Nanua S, Zhou Y, Hennrick KT, Tsai WC, Bentley JK, Lukacs NW, Johnston SL, Hershenson MB. Human rhinovirus 1B exposure induces PI 3-kinase-dependent airway inflammation in mice. Am J Respir Crit Care Med 177:1111-21, 2008. DOI: 10.1164/rccm.200708-1243OC

  2. Sajjan US, Wang Q, Zhao Y, Gruenert DC, Hershenson MB. Rhinovirus disrupts barrier function of polarized airway epithelial cells. Am J Respir Crit Care Med 178:1271-81, 2008. DOI: 10.1164/rccm.200801-136OC

  3. Nagarkar DR, Bowman ER, Schneider D, Wang Q, Shim J, Zhao Y, Linn MJ, McHenry CL, Bentley JK, Tsai WC, Lukacs NW and Hershenson MB. Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol 185:2525-35, 2010. DOI: 10.4049/jimmunol.1000286

  4. Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB. MDA5 and TLR3 signaling initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness. PLoS Pathog. 7:e1002070, 2011. DOI: 10.1371/journal.ppat.1002070

  5. Bentley JK, Sajjan US, Dzaman MB, Jarjour NN, Lee W-M, Gern JE, Hershenson MB. Rhinovirus colocalizes with CD68- and CD11b-positive macrophages after experimental infection in humans. J Allergy Clin Immunol 132:758-761, 2013. DOI: 10.1016/j.jaci.2013.04.020

  6. Hong JY, Bentley JK, Chung Y, Lei J, Steenrod JM, Chen Q, Sajjan US, Hershenson MB. Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness via IL-25 and type 2 innate lymphoid cells. J Allergy Clin Immunol 134:429-39, 2014. DOI: 10.1016/j.jaci.2014.04.020

  7. Han M, Chung Y, Hong JY, Rajput C, Lei J, Hinde JL, Chen Q, Weng S, Bentley JK, Hershenson MB. TLR2-expressing macrophages are required and sufficient for rhinovirus-induced airway inflammation. J Allergy Clin Immunol. 138:1619-1630, 2016. DOI: 10.1016/j.jaci.2016.01.037

  8. Han M, Hong JY, Jaipalli S, Rajput C, Lei J, Hinde JL, Chen Q, Hershenson NM, Bentley JK, Hershenson MB. IFN-γ blocks development of an asthma phenotype in rhinovirus-infected baby mice by inhibiting ILC2s. Am J Respir Cell Mol Biol. 56: 242-241, 2017. DOI: 10.1165/rcmb.2016-0056OC

  9. Rajput C, Cui T, Han M, Lei J, Hinde JL, Wu Q, Bentley JK, Hershenson MB. RORα-dependent type 2 innate lymphoid cells are required and sufficient for mucous metaplasia in immature mice. Am J Physiol Lung Cell Mol Physiol. 312: L983-L993, 2017. DOI: 10.1152/ajplung.00368.2016

  10. Han M, Rajput C, Hong JY, Lei J, Hinde JL, Wu Q, Bentley JK, Hershenson MB. The innate cytokines IL-25, IL-33 and TSLP cooperate in the induction of ILC2 expansion and mucous metaplasia in rhinovirus-infected immature mice. J Immunol. 199:1308-1318, 2017. DOI: 10.4049/jimmunol.1700216

  11. Rajput C, Mingyuan H, Bentley JK, Lei L, Tomoko I, Qian W, Hinde JL, Callear AP, Stillwell TL, Jackson WT, Martin ET, Hershenson MB. Enterovirus D68 infection induces IL-17-dependent neutrophilic airway inflammation and hyperresponsiveness, JCI Insight 2018;3(16). e121882. DOI: 10.1172/jci.insight.121882

  12. Lewis TC, Metitiri EE, Mentz GB, Ren X, Goldsmith AM, Eder BN, Wicklund KE, Walsh MP, Comstock AT, Ricci JM, Brennan SR, Washington GL, Owens KB, Mukherjee B, Robins TG, Batterman SA, Hershenson MB. Influence of viral infection on the relationships between airway cytokines and lung function in asthmatic children. Respir Res 19:228, 2018. DOI: 10.1186/s12931-018-0922-9

  13. Bentley JK, Han M, Jaipalli S, Hinde J, Lei J, Ishikawa T, Goldsmith AM, Rajput C, Hershenson MB. Myristoylated rhinovirus VP4 protein activates TLR2-dependent pro-inflammatory gene expression. Am J Physiol: Lung Cell Mol Physiol 2019; 317:L57-L70. DOI: 10.1152/ajplung.00365.2018

  14. Han M, Bentley JK, Rajput C, Lei J, Ishikawa T, Jarman CR, Lee J, Goldsmith AM, Jackson WT, Hoenerhoff MJ, Lewis TC, Hershenson MB. Inflammasome activation is required for human rhinovirus-induced airway inflammation in naïve and allergen-sensitized mice. Mucosal Immunol 2019; 12:958-968. DOI: 10.1038/s41385-019-0172-2

  15. Han M, Ishikawa T, Bermick JR, Rajput C, Lei J, Goldsmith AM, Jarman CR, Lee J, Bentley JK, Hershenson MB. IL-1β prevents ILC2 expansion, type 2 cytokine secretion and mucus metaplasia in response to early-life rhinovirus infection in mice. Allergy 2020 ;75(8):2005-2019. DOI: 10.1111/all.14241

  16. Rajput C, Han M, Ishikawa T, Lei J, Jazaeri S, Bentley JK, Hershenson MB. Early life heterologous rhinovirus infections induce an exaggerated asthma-like phenotype. J Allergy Clin Immunol 2020;146(3):571-582.e3. DOI: 10.1016/j.jaci.2020.03.039